Pre-diagnostic Circulating Parathyroid Hormone Concentration and Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
نویسندگان
چکیده
Veronika Fedirko*, Elio Riboli, H. Bas Bueno-de-Mesquita, Sabina Rinaldi, Tobias Pischon, Teresa Norat, Eugène H.J.M. Jansen, Fränzel J.B. van Duijnhoven, Anne Tjønneland, Anja Olsen, Kim Overvad, Marie-Christine BoutronRuault, Françoise Clavel-Chapelon, Pierre Engel, Rudolf Kaaks, Birgit Teucher, Heiner Boeing, Brian Buijsse, Antonia Trichopoulou, Dimitrios Trichopoulos, Pagona Lagiou, Sabina Sieri, Paolo Vineis, Salvatore Panico, Domenico Palli, Rosario Tumino, Carla H van Gils, Petra HM Peeters, Maria-Dolores Chirlaque, Aurelio Barricarte Gurrea, Laudina Rodríguez, Esther Molina-Montes, Miren Dorronsoro, Catalina Bonet, Richard Palmqvist, Göran Hallmans, Timothy J. Key, Konstantinos K Tsilidis, Kay-Tee Khaw, Isabelle Romieu, Kurt Straif, Petra A. Wark, Dora Romaguera, Mazda Jenab
منابع مشابه
Pre-diagnostic meat and fibre intakes in relation to colorectal cancer survival in the European Prospective Investigation into Cancer and Nutrition.
Improvements in colorectal cancer (CRC) detection and treatment have led to greater numbers of CRC survivors, for whom there is limited evidence on which to provide dietary guidelines to improve survival outcomes. Higher intake of red and processed meat and lower intake of fibre are associated with greater risk of developing CRC, but there is limited evidence regarding associations with surviva...
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Adults from ten European countries have been questioned about their dietary habits and lifestyles since 1992 for the EPIC trial (European Prospective Investigation into Cancer and Nutrition). Epidemiologists at the International Agency for Research on Cancer (IARC) in Lyon, France, which coordinates EPIC, and colleagues from other EPIC study centres, assessed the relationship between meat and f...
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BACKGROUND Parathyroid hormone (PTH) has been proposed to play a promoting role in carcinogenesis. However, no epidemiologic studies have yet directly investigated its role in colorectal cancer (CRC). METHODS A case-control study nested within the European Prospective Investigation into Cancer and Nutrition cohort was conducted with 1,214 incident, sporadic CRC cases matched to 1,214 controls...
متن کاملLeptin and soluble leptin receptor in risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition cohort.
Leptin, a peptide hormone produced primarily by the adipocytes, is hypothesized to play a role in the pathogenesis of colorectal cancer (CRC). Soluble leptin receptor (sOB-R) may regulate leptin's physiologic functions; however its relation to CRC risk is unknown. This study explored the association of leptin and sOB-R with risk of CRC in a prospective nested case-control study within the Europ...
متن کاملAssociation between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations:a nested case-control study
OBJECTIVE To examine the association between pre-diagnostic circulating vitamin D concentration, dietary intake of vitamin D and calcium, and the risk of colorectal cancer in European populations. DESIGN Nested case-control study. Setting The study was conducted within the EPIC study, a cohort of more than 520 000 participants from 10 western European countries. PARTICIPANTS 1248 cases of i...
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